HUMAN IMMUNODEFICIENCY VIRUS INFECTION – CLINICAL MANIFESTATIONS (OTHER GROUPS)

Subgroup В—Neurological disease

Defined as encephalopathy which can be progressive and may cause dementia, aseptic meningitis, myelopathy or peripheral or autonomic neuropathy.

Subgroup С

Denned as the presence of a disease at least moderately indicative of a defect in cell mediated immunity. These are divided in subgroups:

C-l: Patients with disease due to one of the organisms listed in the surveillance definition of AIDS viz Pneumocystis carinii pneumonia, chronic cryptosporidiosis, toxoplasmosis, extraintestinal strongyloidiasis, isosporiasis, candidiasis (oesophageal, bronchial or pulmonary), cryptococcosis, histoplasmosis, Mycobacterium avium-intracellulare (MAI) complex or M kansasii, cytomegalovirus (CMV), chronic mucocutaneous or disseminated HSV infection, progressive multifocal leukoencephalopathy, recurrent salmonella bacteraemia or extrapulmonary tuberculosis.

C-2: Secondary infectious agents not listed above but involving symptomatic or invasive disease e.g. oral candidiasis, oral hairy leukoplakia, multidermatomal herpes zoster, nocardiosis or pulmonary tuberculosis.

Subgroup D—Secondary cancers

Denned as the presence of a cancer associated with HIV infection including Kaposi’s sarcoma and extranodal B-cell lymphoma.

*90/56/1*

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